cAMP Monoclonal Antibody - BT-MCA2310

cAMP Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2310-50, BT-MCA2310-100

Citations, Manuals and MSDS Available upon request.

Background: Cyclic adenosine monophosphate (cAMP) plays a key role as an intracellular second messenger for transduction events that follow a number of extracellular signals. The G-Protein Coupled Receptors (GPCR) is the largest family of cell surface receptors. They can be activated by different ligands, such as neurotransmitters, hormones, ions, small molecules, peptides, and other physiological signaling molecules. Typically, the binding of the ligands to its receptor resulting in the activation of G-proteins, in return, activates the effector adenylyl cyclase evoking the production of cAMP. The activation of a protein kinase by cAMP results in the phosphorylation of substrate proteins. Currently successful drugs in marketing have been developed to target these receptors. Among the GPCRs, ~367 receptors are potential drug development targets, but only about 20 have been used to generate therapeutically and commercially successful drugs so far. Because the involvement of cAMP can amplify the response of the ligand binding, the second messenger cAMP has been largely employed to monitor the activation of the GPCR to facilitate the therapeutic drug discovery

Research Areas: Others

Target Protein: cAMP

Clonality: Monoclonal

Clone ID: 9H4C4

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: cAMP

Immunogen: cAMP, conjugated to KLH.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

UniProt Accession: P17612

Synonyms: cAMP

Research Use Only