Product Description

CAN1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14639-20, BT-AP14639-50, BT-AP14639-100

Citations, Manuals and MSDS Available upon request.

Background: The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.

Research Areas: Cell biology; Signal transduction

Target Protein: CAPN1

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Calpain-1 catalytic subunit

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P07384; Mouse: O35350; Rat: P97571

Synonyms: Calpain-1 catalytic subunit;EC 3.4.22.52;Calcium-activated neutral proteinase 1;CANP 1;Calpain mu-type;Calpain-1 large subunit;Cell proliferation-inducing gene 30 protein;Micromolar-calpa

GeneID: Human: 823

Research Use Only