Product Description

CAN6 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA31385-50, RA31385-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: calpain 6 (CAPN6) Homo sapiens Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis. [provided by RefSeq, Nov 2009],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 70

Protein Molecular Weight (kDa): 70

Storage: -20°C/1 year

Human Gene ID: 827

Human SwissProt Number: Q9Y6Q1

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only