CARM1 Monoclonal Antibody - BT-MCA4454

CARM1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4454-50, BT-MCA4454-100

Citations, Manuals and MSDS Available upon request.

Background: Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation (Frankel et al. 2002 (PubMed 11724789). Tissue specificity: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia.

Research Areas: Epigenetics and nuclear signaling, Cell biology, Cancer, Metabolism, Signal transduction

Target Protein: CARM1

Applications: WB, IHC, ICC, FCM

Reactivity: Human, Monkey, Rat

Clonality: Monoclonal

Clone ID: 3H2

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CARM1

Immunogen: Purified recombinant fragment of human CARM1 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 65kDa

UniProt Accession: Q86X55

Synonyms: PRMT4, CARM1

GeneID: 10498

Research Use Only