Product Description

CASL Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP07109-20, BT-AP07109-50, BT-AP07109-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants.

Research Areas: Cancer; Cell biology; Epigenetics and nuclear signaling

Target Protein: NEDD9

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Enhancer of filamentation 1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q14511; Mouse: O35177

Synonyms: Enhancer of filamentation 1;hEF1;CRK-associated substrate-related protein;CAS-L;CasL;Cas scaffolding protein family member 2;Neural precursor cell expressed developmentally down-regulated p

GeneID: Human: 4739

Research Use Only