CASP6 Monoclonal Antibody - BT-MCA3911

CASP6 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3911-50, BT-MCA3911-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms.

Research Areas: Neuroscience

Target Protein: CASP6

Applications: FCM

Clonality: Monoclonal

Clone ID: 3B7C3

Host: Mouse

Isotype: Mouse IgG2a

Full Product Name: CASP6

Immunogen: Purified recombinant fragment of human CASP6 (AA: 194–293) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 33.3kDa

UniProt Accession: P55212

Synonyms: MCH2

GeneID: 839

Research Use Only