CASQ2 Rabbit pAb - A16797

CASQ2 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A16797-20, A16797-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.

Category: Polyclonal Antibodies

Applications: WB, IHC-P, ELISA

Cross-reactivity: Mouse, Rat

Protein Weight: 46kDa

Observed Molecular Weight: 46kDa

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 845

SWISS: O14958

Alternate Names: PDIB2; CASQ2

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:100 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Neuroscience, Calcium Signaling, Cardiovascular, Heart, Cardiac arrhythmias.

NCBI Alias: CASQ2

Research Use Only