Cav2.2 Polyclonal Antibody - BT-AP07166

Cav2.2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP07166-20, BT-AP07166-50, BT-AP07166-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene.

Research Areas: Signal transduction

Target Protein: CACNA1B

Applications: IHC-p, IF

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Voltage-dependent N-type calcium channel subunit alpha-1B

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q00975; Mouse: O55017; Rat: Q02294

Synonyms: Voltage-dependent N-type calcium channel subunit alpha-1B;Brain calcium channel III;BIII;Calcium channel, L type, alpha-1 polypeptide isoform 5;Voltage-gated calcium channel subunit alpha Cav2.; Voltage-dependent N-type calcium channel subunit alpha-1B; Brain calcium channel III; BIII; Calcium channel, L type, alpha-1 polypeptide isoform 5; Voltage-gated calcium channel subunit alpha Cav2.2

GeneID: Human: 774

Research Use Only