CBS Rabbit pAb - A1427

CBS Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A1427-20, A1427-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene.

Category: Polyclonal Antibodies

Applications: WB, IF-P, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 61kDa

Observed Molecular Weight: 61kDa

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 875

SWISS: P35520

Alternate Names: CBSL; HIP4; CBS

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 IF-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Amino acid metabolism.

NCBI Alias: CBS

Research Use Only