CBX1 Monoclonal Antibody - BT-MCA3914

CBX1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3914-50, BT-MCA3914-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Research Areas: Epigenetics and nuclear signaling

Target Protein: CBX1

Applications: WB, ICC, FCM

Reactivity: Human, Monkey

Clonality: Monoclonal

Clone ID: 5A3

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CBX1

Immunogen: Purified recombinant fragment of human CBX1 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 21kDa

UniProt Accession: P83916

Synonyms: CBX, M31, MOD1, p25beta, HP1-BETA, HP1Hsbeta, HP1Hs-beta, CBX1

GeneID: 10951

Research Use Only