CC14B Polyclonal Antibody - BT-AP14727

CC14B Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14727-20, BT-AP14727-50, BT-AP14727-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.

Research Areas: Cell biology; Signal transduction

Target Protein: CDC14B

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Dual specificity protein phosphatase CDC14B

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O60729; Mouse: Q6PFY9

Synonyms: Dual specificity protein phosphatase CDC14B;EC 3.1.3.16;EC 3.1.3.48;CDC14 cell division cycle 14 homolog B

GeneID: Human: 8555

Research Use Only