CCAR1 Polyclonal Antibody - BT-AP14733

CCAR1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14733-20, BT-AP14733-50, BT-AP14733-100

Citations, Manuals and MSDS Available upon request.

Background: May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence Contaminating sequence. Potential poly-A sequence.,Contains 1 SAP domain.,tissue specificity:Expressed in various epithelial cancer cell lines, including breast, colon, prostate, pancreatic and leukemia. Expression is regulated by growth factors.,

Research Areas: Epigenetics and nuclear signaling

Target Protein: CCAR1

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Cell division cycle and apoptosis regulator protein 1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q8IX12; Mouse: Q8CH18

Synonyms: Cell division cycle and apoptosis regulator protein 1;Cell cycle and apoptosis regulatory protein 1;CARP-1;Death inducer with SAP domain

GeneID: Human: 55749

Research Use Only