Product Description

CCDC7 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS65410-50, BS65410-100

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Swiss-Prot: Q96M83

Host: Rabbit

Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Horse,

Applications: WB

All Applications: WB=1:500-2000

Background: The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. Some proteins that contain coil-coiled domains include c-jun, c-fos and tropomyosin. Coiled-coil domains consist of two or more ?helices packed together via interlacing side chains. CCDC7 (Coiled-coil domain-containing protein 7) is a 486 amino acid protein that contains a coiled-coil domain and is encoded by a gene that maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman抯 syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria. There are two isoforms of CCDC7 that are produced as a result of alternative splicing events.

Purification and Purity: affinity purified by Protein A

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CCDC7 Polyclonal Antibody detects endogenous levels of CCDC7 protein.

Bioworld Molecular Weight: 56 kD

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Primary: Anti- CCDC7 (bs-7991R) at 1/1000 dilution

Alternative Name: BioT2 A; BioT2 B; BioT2 C; CCDC 7; Coiled coil domain containing 7; Coiled coil domain containing protein 7; CCDC7_HUMAN.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC7:155-250/486

Conjugate: Unconjugated

Modification: Unmodified