CCR10 Monoclonal Antibody - BT-MCA2860

CCR10 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2860-50, BT-MCA2860-100

Citations, Manuals and MSDS Available upon request.

Background: Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008]

Research Areas: Immunology

Target Protein: CCR10

Applications: IHC, ICC, FCM

Clonality: Monoclonal

Clone ID: 6E3E4

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CCR10

Immunogen: Purified recombinant fragment of human CCR10 (AA: extra mix) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 38.4kDa

UniProt Accession: P46092

Synonyms: GPR2

GeneID: 2826

Research Use Only