CD105/Endoglin Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A5639-20, A5639-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 71kDa
Observed Molecular Weight: 100kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 2022
SWISS: P17813
Alternate Names: END; HHT1; ORW1; CD105/Endoglin
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Tumor biomarkers, Immunology Inflammation, CDs, Stem Cells, Mesenchymal Stem Cells, Cardiovascular.
NCBI Alias: ENG
Research Use Only