CD118 Monoclonal Antibody - BT-MCA2190

CD118 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2190-50, BT-MCA2190-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding two different isoforms have been found for this gene.

Research Areas: Others

Target Protein: CD118

Clonality: Monoclonal

Clone ID: 8E9D3

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CD118

Immunogen: Purified recombinant fragment of human PLA2G7 (AA: 22-441) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 123.7kDa

UniProt Accession: P42702

Synonyms: LIFR, SWS, SJS2, STWS, LIF-R

GeneID: 3977

Research Use Only