CD11a Monoclonal Antibody - BT-MCA4341

CD11a Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4341-50, BT-MCA4341-100

Citations, Manuals and MSDS Available upon request.

Background: ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.

Research Areas: Others

Target Protein: CD11a

Applications: WB, IHC, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 5G7C5

Host: Mouse

Isotype: Mouse IgG2a

Full Product Name: CD11a

Immunogen: Purified recombinant fragment of human CD11a (AA: extra 26-194) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 128.8kDa

UniProt Accession: P20701

Synonyms: ITGAL, LFA-1, LFA1A

GeneID: 3683

Research Use Only