CD120B Monoclonal Antibody - BT-MCA2492

CD120B Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2492-50, BT-MCA2492-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.

Research Areas: Others

Target Protein: CD120B

Applications: WB, FCM

Reactivity: Human, Mouse

Clonality: Monoclonal

Clone ID: 2H11C2

Host: Mouse

Isotype: Mouse IgG2b

Full Product Name: CD120B

Immunogen: Purified recombinant fragment of human CD120B (AA: extra 23-257) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 48.3kDa

UniProt Accession: P20333

Synonyms: TNFRSF1B, p75, TBPII, TNFBR, TNFR2, TNFR1B, TNFR80, TNF-R75, p75TNFR, TNF-R-II

GeneID: 7133

Research Use Only