CD121B Monoclonal Antibody - BT-MCA3830

CD121B Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3830-50, BT-MCA3830-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.

Research Areas: Others

Target Protein: CD121B

Applications: ICC, FCM

Clonality: Monoclonal

Clone ID: 5D7B1

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CD121B

Immunogen: Purified recombinant fragment of human CD121B (AA: extra 14-343) expressed in HEK293-6e cells supernatant.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 45.4kDa

UniProt Accession: P27930

Synonyms: IL1R2, IL1RB, IL1R2c, CDw121b, IL-1R-2, IL-1RT2, IL-1RT-2

GeneID: 7850

Research Use Only