CD126 Monoclonal Antibody - BT-MCA2031

CD126 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2031-50, BT-MCA2031-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been identified in this gene. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, Aug 2020]

Research Areas: Others

Target Protein: CD126

Applications: WB, IHC, ICC, FCM

Clonality: Monoclonal

Clone ID: 8F7G6

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CD126

Immunogen: Purified recombinant fragment of human CD126 (AA: EXTRA 20-177) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 52kDa

UniProt Accession: P08887

Synonyms: IL6Q, gp80, CD126, HIES5, IL-6R, IL6RA, IL6RQ, IL-1Ra, IL-6RA, IL6QTL, IL-6R-1

GeneID: 3570

Research Use Only