CD130 Monoclonal Antibody - BT-MCA2751

CD130 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2751-50, BT-MCA2751-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014]

Research Areas: Others

Target Protein: CD130

Applications: WB, IHC, ICC, FCM

Reactivity: Human, Monkey

Clonality: Monoclonal

Clone ID: 8D4D2

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CD130

Immunogen: Purified recombinant fragment of human CD130 (AA: extra 73-231) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 103.5kDa

UniProt Accession: P40189

Synonyms: IL6ST, GP130, CDW130, IL-6RB

GeneID: 3572

Research Use Only