CD133 Monoclonal Antibody - BT-MCA0273

CD133 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0273-50, BT-MCA0273-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Areas: Neuroscience; Stem cells

Target Protein: PROM1

Applications: IHC-p, IF, FCM, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Prominin-1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O43490; Mouse: O54990

Synonyms: PROM1; Prominin-1; Antigen AC133; Prominin-like protein 1; CD antigen CD133

GeneID: Human: 8842

Research Use Only