CD137 Monoclonal Antibody - BT-MCA4140

CD137 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4140-50, BT-MCA4140-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.

Research Areas: Others

Target Protein: CD137

Applications: WB, FCM

Clonality: Monoclonal

Clone ID: 2A12C2

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CD137

Immunogen: Purified recombinant fragment of human CD137 (AA: 214-255) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 27.9kDa

UniProt Accession: Q07011

Synonyms: TNFRSF9, ILA, 4-1BB, CDw137

GeneID: 3604

Research Use Only