CD148 Monoclonal Antibody - BT-MCA2114

CD148 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2114-50, BT-MCA2114-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Areas: Others

Target Protein: CD148

Applications: FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 6F2E12

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CD148

Immunogen: Purified recombinant fragment of human CD148 (AA: extra 36-210) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 146kDa

UniProt Accession: Q12913

Synonyms: PTPRJ, DEP1, SCC1, HPTPeta, R-PTP-ETA

GeneID: 5795

Research Use Only