CD162 Monoclonal Antibody - BT-MCA4819

CD162 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4819-50, BT-MCA4819-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.

Research Areas: Others

Target Protein: CD162

Applications: IHC, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 3D5H1

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CD162

Immunogen: Purified recombinant fragment of human CD162(AA: 42-320) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 43.2kDa

UniProt Accession: Q14242

Synonyms: CLA, PSGL1, PSGL-1

GeneID: 6404

Research Use Only