CD170 Monoclonal Antibody - BT-MCA4028

CD170 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4028-50, BT-MCA4028-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.

Research Areas: Others

Target Protein: CD170

Applications: FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 3F5A3

Host: Mouse

Isotype: Mouse IgG2a

Full Product Name: CD170

Immunogen: Purified recombinant fragment of human CD170 (AA: extra 17-230) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 60.7kDa

UniProt Accession: O15389

Synonyms: SIGLEC5, OBBP2, CD33L2, OB-BP2, SIGLEC-5

GeneID: 8778

Research Use Only