CD171 Monoclonal Antibody - BT-MCA4143

CD171 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4143-50, BT-MCA4143-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.

Research Areas: Others

Target Protein: CD171

Applications: FCM

Clonality: Monoclonal

Clone ID: 5C6A10

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CD171

Immunogen: Purified recombinant fragment of human CD171 (AA: 20-197) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 140kDa

UniProt Accession: P32004

Synonyms: L1CAM, S10, HSAS, MASA, MIC5, SPG1, CAML1, HSAS1, N-CAML1, NCAM-L1, N-CAM-L1

GeneID: 3897

Research Use Only