CD172b Monoclonal Antibody - BT-MCA4505

CD172b Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4505-50, BT-MCA4505-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Areas: Others

Target Protein: CD172b

Applications: FCM

Clonality: Monoclonal

Clone ID: 1A1F4

Host: Mouse

Isotype: Mouse IgG2b

Full Product Name: CD172b

Immunogen: Purified recombinant fragment of human CD172b (AA: extra 72-309) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 43.2kDa

UniProt Accession: O00241

Synonyms: SIRPB1, SIRP-BETA-1

GeneID: 10326

Research Use Only