CD177 Monoclonal Antibody - BT-MCA2208

CD177 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2208-50, BT-MCA2208-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.

Research Areas: Immunology

Target Protein: CD177

Applications: WB, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 2F2C1

Host: Mouse

Isotype: Mouse IgG2b

Full Product Name: CD177

Immunogen: Purified recombinant fragment of human CD177 (AA: extra 22-161) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 46.4kDa

UniProt Accession: Q8N6Q3

Synonyms: NB1, PRV1, HNA2A, PRV-1, HNA-2a, NB1 GP

GeneID: 57126

Research Use Only