CD178 Monoclonal Antibody - BT-MCA3829

CD178 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3829-50, BT-MCA3829-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.

Research Areas: Others

Target Protein: CD178

Applications: ICC, FCM

Clonality: Monoclonal

Clone ID: 2A6E12

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CD178

Immunogen: Purified recombinant fragment of human CD178 (AA: extra 103-281) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 31.5kDa

UniProt Accession: P48023

Synonyms: FASLG, APTL, FASL, CD95L, ALPS1B, CD95-L, TNFSF6, TNLG1A, APT1LG1

GeneID: 356

Research Use Only