CD18 Monoclonal Antibody - BT-MCA2108

CD18 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2108-50, BT-MCA2108-100

Citations, Manuals and MSDS Available upon request.

Background: CD18, also known as ITGB2 (integrin beta chain beta 2). Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. CD18 is expressed by most leucocytes. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.

Research Areas: Others

Target Protein: CD18

Applications: ICC

Reactivity: Human, Mouse

Clonality: Monoclonal

Clone ID: 10E12

Host: Mouse

Isotype: Mouse IgG2b

Full Product Name: CD18

Immunogen: Purified recombinant fragment of CD18 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 85kDa

UniProt Accession: P05107

Synonyms: LAD, MF17, LCAMB, LFA-1, ITGB2

GeneID: 3689

Research Use Only