CD192 Monoclonal Antibody - BT-MCA4443

CD192 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4443-50, BT-MCA4443-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3.

Research Areas: Others

Target Protein: CD192

Applications: WB, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 3B6B1

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CD192

Immunogen: Purified recombinant fragment of human CD192 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 41.9kDa

UniProt Accession: P41597

Synonyms: CCR2, CKR2, CCR-2, CCR2A, CCR2B, CKR2A, CKR2B, CMKBR2, MCP-1-R, CC-CKR-2

GeneID: 729230

Research Use Only