CD1B Polyclonal Antibody - E-AB-17775

CD1B Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-17775-60, E-AB-17775-120, E-AB-17775-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD1B

Target Synonym: A1 domain; CD1; CD1A; CD1b; CD1b antigen; CD1B antigen b polypeptide; CD1b molecule; CD1B; Cortical thymocyte antigen CD1A; Cortical thymocyte antigen CD1B; Differentiation antigen CD1 alpha 3; hTa1 thymocyte antigen; Ly38; Ly38; T cell surface glycoprotein CD1a; MGC125990; MGC125991; R1; T-cell surface glycoprotein CD1b; T6/Leu6; Thymocite antigen CD1B

Research Areas: Cancer, Immunology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P29016

Background: CD1B (CD1b Molecule) is a Protein Coding gene. Diseases associated with CD1B include Mycobacterium Malmoense and Immune System Organ Benign Neoplasm. Among its related pathways are Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell and Innate Immune System. GO annotations related to this gene include beta-2-microglobulin binding and endogenous lipid antigen binding. An important paralog of this gene is CD1C.This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.

Concentration: 1.4 mg/mL

Immunogen: Synthetic peptide of human CD1B

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only