CD210 Monoclonal Antibody - BT-MCA3681

CD210 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3681-50, BT-MCA3681-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

Research Areas: Others

Target Protein: CD210

Applications: FCM

Clonality: Monoclonal

Clone ID: 4D3A9

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CD210

Immunogen: Purified recombinant fragment of human CD210 (AA: extra 22-235) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 63kDa

UniProt Accession: Q13651

Synonyms: IL10RA, IL10R, CD210a, CDW210A, HIL-10R, IL-10R1

GeneID: 3587

Research Use Only