CD220 Monoclonal Antibody - BT-MCA4094

CD220 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4094-50, BT-MCA4094-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.

Research Areas: Others

Target Protein: CD220

Applications: FCM

Clonality: Monoclonal

Clone ID: 1A1G3

Host: Mouse

Isotype: Mouse IgG2a

Full Product Name: CD220

Immunogen: Purified recombinant fragment of human CD220 (AA: extra 413-624) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 156kDa

UniProt Accession: P06213

Synonyms: INSR, HHF5

GeneID: 3643

Research Use Only