CD222 Monoclonal Antibody - BT-MCA4667

CD222 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4667-50, BT-MCA4667-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015]

Research Areas: Others

Target Protein: CD222

Applications: FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 4F1G1

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CD222

Immunogen: Purified recombinant fragment of human CD222 (AA: 160-311) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 274kDa

UniProt Accession: P11717

Synonyms: IGF2R, MPR1, MPRI, CIMPR, M6P-R, MPR300, CI-M6PR, MPR 300, M6P/IGF2R

GeneID: 3482

Research Use Only