Product Description

CD232 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES4357-50, ES4357-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2011],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Alternate Names: PLXNC1, VESPR, Plexin-C1, Virus-encoded semaphorin protein receptor, CD232

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human PLXNC1. AA range:811-860

Isotype: IgG

Target: CD232

Specificity: CD232 Polyclonal Antibody detects endogenous levels of CD232 protein.

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Detected in heart, brain, lung, spleen and placenta,

Observed Band (KD): 175kD

Fields: Axon guidance

Function: Function: Receptor for vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of viral semaphorins triggers cellular responses leading to the rearrangement of the cytoskeleton and to secretion of IL6 and IL8
PTM: N-glycosylated
Similarity: Belongs to the plexin family
Similarity: Contains 1 Sema domain
Tissue Specificity: Detected in heart, brain, lung, spleen and placenta

Subcellular Location: Membrane, Single-pass type I membrane protein

Storage and Stability: -20°C/1 year

Gene Name: PLXNC1

Protein Name: Plexin-C1

Mouse Gene ID: 54712

Mouse SwissProt Number: Q9QZC2

Research Use Only