CD239/BCAM Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A14747-20, A14747-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms: AU; LU; CD239; MSK19; CD239/BCAM
GeneID: 4059
Swiss-Prot: P50895
Reactivity: Mouse
Tested Applications: ELISA, WB
Calculated Molecular Weight: 67kDa
Observed Molecular Weight: 90kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 352-547 of human CD239/CD239/BCAM (NP_005572.2).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Research Areas: Immunology Inflammation, CDs, Cardiovascular, Blood
Recommended Dilutions: WB: 1:500 - 1:2000
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Membrane, Single-pass Type I Membrane Protein
Positive Samples: Mouse lung
Keywords: 4059, BCAM, AU, CD239, LU, MSK19, basal cell adhesion molecule (Lutheran blood group), basal cell adhesion molecule, Auberger b antigen, B-CAM cell surface glycoprotein, B-cell adhesion molecule, F8/G253 antigen, Lutheran blood group variant LUGA, basal cell adhesion molecule (Lu and Au blood groups), P50895, Basal Cell Adhesion Molecule (Lutheran Blood Group), Basal Cell Adhesion Molecule (Lu And Au Blood Groups), B-CAM Cell Surface Glycoprotein, Auberger B Antigen, F8/G253 Antigen, Lutheran Blood Group (Auberger B Antigen Included), Lutheran Blood Group Variant LUGA, Lutheran Blood Group Glycoprotein, Basal Cell Adhesion Molecule, B-Cell Adhesion Molecule, Lutheran Antigen, CD239 Antigen, CD239/BCAM
Symbol: BCAM
Category: Polyclonal Antibodies
Research Use Only