CD27 Monoclonal Antibody - BT-MCA4261

CD27 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4261-50, BT-MCA4261-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

Research Areas: Cancer, Immunology, Stem cells

Target Protein: CD27

Applications: FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 3B6D3

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CD27

Immunogen: Purified recombinant fragment of human CD27 (AA: extra 20-144) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 29.1kDa

UniProt Accession: P26842

Synonyms: T14, S152, Tp55, TNFRSF7, S152. LPFS2

GeneID: 939

Research Use Only