CD276/B7-H3 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A17216-20, A17216-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human
Protein Weight: 57kDa
Observed Molecular Weight: 90kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 80381
SWISS: Q5ZPR3
Alternate Names: B7H3; B7-H3; B7RP-2; 4Ig-B7-H3; CD276/B7-H3
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Tumor biomarkers, Immunology Inflammation, CDs, Stem Cells, Hematopoietic Progenitors.
NCBI Alias: CD276
Research Use Only