CD282 Monoclonal Antibody - BT-MCA3522

CD282 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3522-50, BT-MCA3522-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants.

Research Areas: Others

Target Protein: CD282

Reactivity: Human

Clonality: Monoclonal

Clone ID: 7C1H9

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CD282

Immunogen: Purified recombinant fragment of human CD282 (AA: extra 21-197) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 89.8kDa

UniProt Accession: O60603

Synonyms: TLR2, TIL4

GeneID: 7097

Research Use Only