CD289 Monoclonal Antibody - BT-MCA3893

CD289 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3893-50, BT-MCA3893-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.

Research Areas: Others

Target Protein: CD289

Applications: FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 5B10E8

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CD289

Immunogen: Purified recombinant fragment of human CD289 (AA: extra 26-193) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 116kDa

UniProt Accession: Q9NR96

Synonyms: TLR9

GeneID: 54106

Research Use Only