Product Description

CD2AP Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA31501-50, RA31501-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: CD2 associated protein (CD2AP) Homo sapiens This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 70

Protein Molecular Weight (kDa): 70

Storage: -20°C/1 year

Human Gene ID: 23607

Human SwissProt Number: Q9Y5K6

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only