CD321 Monoclonal Antibody - BT-MCA3042

CD321 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3042-50, BT-MCA3042-100

Citations, Manuals and MSDS Available upon request.

Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

Research Areas: Others

Target Protein: CD321

Applications: IHC, FCM

Clonality: Monoclonal

Clone ID: 1B7C5

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CD321

Immunogen: Purified recombinant fragment of human CD321 (AA: extra 28-238) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 32.6kDa

UniProt Accession: Q9Y624

Synonyms: F11R, JAM, KAT, JAM1, JAMA, JCAM, PAM-1

GeneID: 50848

Research Use Only