CD338 Monoclonal Antibody - BT-MCA4425

CD338 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4425-50, BT-MCA4425-100

Citations, Manuals and MSDS Available upon request.

Background: The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Areas: Others

Target Protein: CD338

Applications: WB, IHC, ICC, FCM

Clonality: Monoclonal

Clone ID: 4H3C10

Host: Mouse

Isotype: Mouse IgG2b

Full Product Name: CD338

Immunogen: Purified recombinant fragment of human CD338 (AA: extra mix) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 75kDa

UniProt Accession: Q9UNQ0

Synonyms: MRX, MXR, ABCP, BCRP, BMDP, MXR1, ABC15, BCRP1, ABCG2, GOUT1, MXR-1, CDw338, UAQTL1, EST157481

GeneID: 9429

Research Use Only