CD360 Monoclonal Antibody - BT-MCA3510

CD360 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3510-50, BT-MCA3510-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.

Research Areas: Others

Target Protein: CD360

Applications: FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 8H10G4D12

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CD360

Immunogen: Purified recombinant fragment of human CD360 (AA: extra 20-232) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 59.1kDa

UniProt Accession: Q9HBE5

Synonyms: IL21R, NILR, IMD56

GeneID: 50615

Research Use Only