Product Description

CD37 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: NCP0203P-50, NCP0203P-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: CD37 belongs to the tetraspanin family of transmembrane proteins and a high level of expression is restricted largely to normal and as well as malignant B cells. Other immune cell popμlations such as T cells and monocytes, however, have been shown to express low levels of CD37. While the molecμlar mechanisms are still not fμlly resolved, research studies have shown that CD37 becomes tyrosine phosphorylated and facilitates association with intracellμlar signaling proteins that drive both survival and apoptosis in B cells. Due to its fairly restricted, high level of expression in normal and neoplastic B cells, CD37 has become an attractive immunotherapy target in the context of B cells malignancies.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IF

Alternate Names: Leukocyte antigen CD37, Tetraspanin-26, Tspan-26, CD37, TSPAN26

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Recombinant protein of human CD37.

Dilution: WB: 1:2000~1:5000
IF 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CD37 polyclonal antibody detects endogenous levels of CD37 protein.

Molecular Weight: ~ 43 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P11049

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Research Use Only