CD38 Monoclonal Antibody - BT-MCA3107

CD38 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3107-50, BT-MCA3107-100

Citations, Manuals and MSDS Available upon request.

Background: CD38 is a type II integral membrane glycoprotein which is present on early B and T cell lineages and activated B and T cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B cells, mitogen-activated T cells, monocytes and Ig-secreting plasma cells. CD38 acts as a NAD glycohydrolase in T lym- phocytes. On hematopoietic cells CD38 induces activation, proliferation, and differentiation of mature T and B cells and mediates apoptosis of myeloid and lymphoid progenitor cells. In addition to acting as a signaling receptor, CD38 is also an enzyme capable of producing several calcium-mobilizing metabo- lites, including cyclic adenosine diphosphate ribose (cADPR). CD38 also plays a role in maintaining survival of an invariant NK T (iNKT) cell subset that preferentially contributes to the maintenance of immunological tolerance.

Research Areas: Immunology

Target Protein: CD38

Applications: IHC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 6E12D4A12

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CD38

Immunogen: Purified recombinant fragment of human CD38 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 34kDa

UniProt Accession: P28907

Synonyms: T10, CD38

GeneID: 952

Research Use Only