CD4 Monoclonal Antibody - BT-MCA4293

CD4 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4293-50, BT-MCA4293-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Research Areas: Immunology

Target Protein: CD4

Applications: FCM

Clonality: Monoclonal

Clone ID: 3A12A5

Host: Mouse

Isotype: Mouse IgG2b

Full Product Name: CD4

Immunogen: Purified recombinant fragment of human CD4 (AA: 26-170) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 51kDa

UniProt Accession: P01730

Synonyms: IMD79, OKT4D, CD4mut

GeneID: 920

Research Use Only