CD44 Monoclonal Antibody - BT-MCA3322

CD44 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3322-50, BT-MCA3322-100

Citations, Manuals and MSDS Available upon request.

Background: CD44, also known as IN, LHRMIC4, CDW44, HCELL. It is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

Research Areas: Immunology

Target Protein: CD44

Applications: IHC, ICC, FCM

Reactivity: Human, Mouse

Clonality: Monoclonal

Clone ID: 8E2F3

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CD44

Immunogen: Purified recombinant fragment of human CD44 (628-699) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 82kDa

UniProt Accession: P16070

Synonyms: IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, CDW44, CSPG8, HCELL

GeneID: 960

Research Use Only